Saturday, May 7, 2011

Popcorn cell


The popcorn cell is found in a form of lymphoma (malignancy of lymphocytes) known as nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). In this subtype of Hodgkin lymphoma, when tumor tissue sections are seen under the light microscope, some cell nuclei look lobulated resembling popcorn kernels - popcorn cell.
NLPHL is an uncommon form of lymphoma that typically affects males and has a relatively good outcome. Hodgkin lymphoma is named in commemoration of Thomas Hodgkin, a British pathologist, who made early descriptions of this condition.
Reference:
Wlodarska I et al: Frequent occurrence of BCL6 rearrangements in nodular lymphocyte predominance Hodgkin lymphoma but not in classical Hodgkin lymphoma. Blood, 2003 101(2):706-10. Go to reference


Popcorn cell

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